10. Predict the secondary structure of the C-peptide of pro-insulin using the methods of Chou-Fasman and Rose. Is it likely to have supersecondary structure?

EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ

Use EXPASy tools to check your answer

 

12. Indicate the probably effects of the following mutational changes on the structure of a protein. Explain your answer.
(a) changing a Leu to a Phe
(b) changing a Lys to a Glu
(c) changing Val to Thr
(d) changing Gly to Ala
(e) changing Met to Pro